The poison of _Spirochaete pallida_, the microoerganism which causes
syphilis, has been widely credited with a directly noxious effect on the
germ-plasm, and the statement has been made that this effect can be
transmitted for several generations. On the other hand, healthy children
are reported as being born to cured syphilitics. Further evidence is
needed, taking care to eliminate cases of infection from the parents. If
the alleged deterioration really occurs, it will still remain to be
determined if the effect is permanent or an induction, that is, a change
in the germ-cells which does not permanently alter the nature of the
inherited traits, and which would disappear in a few generations under
favorable conditions.
The case against lead is similar. Sir Thomas Oliver, in his _Diseases of
Occupation_, sums up the evidence as follows:
"Rennert has attempted to express in statistical terms the varying
degrees of gravity in the prognosis of cases in which at the moment of
conception both parents are the subjects of lead poisoning, also when
one alone is affected. The malign influence of lead is reflected upon
the fetus and upon the continuation of the pregnancy 94 times out of 100
when both parents have been working in lead, 92 times when the mother
alone is affected, and 63 times when it is the father alone who has
worked in lead.
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