As the dose is large, a site must be selected for the
injection where the tissue is loose, otherwise the pain will interfere
with the desired frequency of use. The buttocks serve best, or the outer
masses of the pectoral muscles, or the abdominal muscles. If the
administration causes pain (due in part to the large quantity used and
in part to the local effect of glycerin), a fraction of a grain of
cocaine may be added to the solution when measured out for use.
It may at once be said, emphatically, that in some cases remarkable
results have followed the use of this material, while in others no good
has been done; but the same may be said of most plans of treatment in
this disorder. As to possible danger from it, no harm has been done to
any patient known to me, except that abcesses have occurred sometimes,
though very rarely, for in many hundreds of injections it has been my
good fortune to see abscesses form only three or four times, two of
these instances, by curious ill luck, being in physicians. Patients
describe a stimulating effect not unlike that of strong coffee,
following a few hours after use and lasting for a day.
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